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Preimplantation Genetic Diagnosis (PGD)

 

What are the pathologies that can be diagnosed by PGD DNA analysis?

 

How is PGD carried out?

- Ovulation Induction
- Oocyte Aspiration
- Fertilization and Embryo Culture
- Polar body removal and/or blastomere biopsy
- Preimplantation Genetic - Diagnosis in blastomeres
- Embryo transfer and implantation

 

Single gene disorders studied and results obtained

 

Preimplantation HLA matching
Embryo transfer and implantation

After mutation analysis of the blastomeres has been completed, once an embryo is predicted to be free from the genetic disease for which testing was performed, embryos resulted without genetic anomalies are transferred to the patient.

Embryo transfer is a 15 minute procedure accomplished by inserting a catheter (preloaded with embryos) into the uterine cavity through the cervical canal.

This procedure is often performed under ultrasound guidance.

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